Target-driven selection in a dynamic nitrone library.

نویسندگان

  • Simon M Turega
  • Christiane Lorenz
  • Jan W Sadownik
  • Douglas Philp
چکیده

Nitrones undergo dynamic exchange in chloroform at room temperature through two mechanisms-hydrolysis and recombination or hydroxylamine addition/elimination; this dynamic exchange is harnessed to select a nitrone-based bis(amidopyridine) receptor for diacids from a group of four nitrones through its binding to a glutaric acid-based target.

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عنوان ژورنال:
  • Chemical communications

دوره 34  شماره 

صفحات  -

تاریخ انتشار 2008